Mesothelioma and Lung cancer:

June 4th, 2007 by admin

The name cancer itself sounds frightening and there is no other disease as perilous and life threatening as cancer except for a few others. Cancer cells are differently natured and once they develop in the body due to any reason there is no telling where they would take the victim. They penetrate like an undefeatable force and the devastation they inflict is beyond easy cure.

 Most cancers are named after the part of the body where the cancer first starts. This type of cancer begins in the tissue that surrounds different organs inside the body. This tissue, called mesothelium, protects organs by making a special fluid that allows the organs to move. Mesothelium surrounds the lungs, stomach, and heart, and tumors can begin in any of these areas. Three quarters of mesothelial tumors begin in the pleura of the lungs, with the remainder in the peritoneum (stomach), and a small number in the heart.For many patients with other forms of lung cancer, this chapter may be better ignored since many statements about mesothelioma will not apply to other forms of lung cancer. The presentation of mesothelioma as well as its treatment vary from non-small cell and small lung cancer. Mesothelioma is a rare cancer which has attracted much attention. First, it is perhaps the only cancer with a clear environmental component. Mesothelioma is directly related to exposure to asbestos with about 80% of mesotheliomas tied to asbestos exposure. From a scientific perspective, the disease is studied to understand how a cancer develops in relation to a specific causative agent. 

 ·          A brief insight to differences in mesothelioma and lung cancer:

CONDITION

MESOTHELIOMA NON-SMALL CELL LUNG CANCER
Initial Presentation A group of nodules in the pleura part of the lung Single nodule
Primary Danger Loss of breathing capacity and serious problems in the lungs themselves Metastasis to lymph nodes, and other organs
Asbestos Primary Cause Limited role
Chemotherapy Frequently applied to the area itself. Given by injection to disseminate throughout the body.
Smoking Small Primary cause
Epidermal Growth Factor Inhibitors and Iressa Clinical trials beginning.Some cell studies discuss the role of EGR. Some efficacy in stabilizing disease for a limited time and improving quality of life.
P-53 Tumor Suppressor Gene Debatable impact, and P-53 genetic damages is not seen in many studies. Regulation of apoptosis is a problem. Significant role in cell repair and apoptosis. P-53 abnormalities significant in non-small lung cancer as well as other cancers.
Surgery   Complex procedure on the pleura, performed only a few specialized facilities, with other treatment modalities. Removal of the nodule. a common procedure.Post-surgical chemotherapy or radiation for stage 1 patients remains experimental.

The Similarities: 

CONDITION OR FEATURE

MESOTHELIOMA NON-SMALL CELL LUNG CANCER
Chemotherapy Platinum-based chemotherapy such as Cisplatin or Carboplatin is the main form. Extends life but does not provide an overall cure. similar
Radiation Effective at local control of tumor and relieving symptoms. Long-term survival benefit is uncertain similar
Surgery Used only for early stage disease Similar

Another look at the staging of mesothelioma:

A physician will look inside the chest cavity with an instrument called a thorocoscope. This test, called thorocoscope, is usually done in the hospital. Before the test, a local anesthetic is given. The physician may also look inside the abdomen (peritoneoscopy) with a special tool called a peritoneoscope. The peritoneoscope is put into an opening made in the abdomen to ascertain the existence of peritoneal mesothelioma. This test is also usually done in the hospital with a local anesthetic. Biopsies are usually done during the thorcoscope or peritoneoscopy.

 The staging of mesothelioma:

Mesothelioma uses a different staging system called the Butchert system using stages one through four to designate the extent of spread of mesothelioma:

Localized Mesotheliom Stage I:

The cancer is found in the lining of the chest cavity near the lung and heart or in the diaphragm or the lung.

Advanced mesothelioma

 Stage II:

The cancer has spread beyond the lining of the chest to lymph nodes in the chest.

Stage III: Cancer has spread into the chest wall, center of the chest, heart, through the diaphragm, or abdominal lining, and in some cases into nearby lymph nodes.

Stage IV: Cancer has spread to distant organs or tissues.

 The staging system was developed so that proper diagnosis of mesothelioma could be made. The International Mesothelioma Interest Group staging system is another name for the TNM staging procedure. This staging is used as a general staging for all types of cancers. It is through this process that the physicians can further decide what steps to take and how is the treatment going to help the patient. The stages tell doctors about the size, location and the intensity of the disease. All these factors combined together can help both you and your doctor in making the journey through the treatment as easy as possible.

Posted in Mesothelioma and Lung cancer: |

One Response

  1. Commercial Roofing Says:

    This blog helps…
    Mesothelioma is due to asbestos.
    These symptoms may be caused by mesothelioma or by other, less serious conditions.

    Mesothelioma that affects the pleura can cause these signs and symptoms:

    * chest wall pain
    * pleural effusion, or fluid surrounding the lung
    * shortness of breath
    * fatigue or anemia
    * wheezing, hoarseness, or cough
    * blood in the sputum (fluid) coughed up

    - I think thats all I can add up.
    - let us be aware —> Commercial Roofing | Residential Roofing

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